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Local infusion directly to tissue is a growing modality for treatment of infection, pain management and chemotherapeutic or other agents.
Twin Star’s proprietary microWelcome to Twin Star Medicalporous hollow fiber catheter technology provides great potential improvement in consistently and uniformly delivering therapeutics to tissue.
Catheter system concepts include possible use in shortWelcome to Twin Star Medicalterm delivery, or longer term indwelling catheter placement for chemotherapy or pain medications over defined treatment regimens.
This drug delivery technology could potentially be used in three broad classes of clinical conditions. Any combination of these three conditions may occur: • Impaired Microcirculation – Conditions such as
ischemia, infection, trauma, or osteoradionecrosis,
where the microcirculation is disrupted and thus the
delivery of blood–borne agents is impaired.
• Systemic Toxicity – Conditions when limitations
on systemic dose, duration, or repetition are
necessary because of systemic toxicity of agents
such as antibiotics or antimetabolites.
• Impermeable, Large, and/or Insoluble
Agents –
Conditions in which large, poorly diffusible
molecules (immunoglobulins, growth factors,
enzymes, and genetic vectors) must be delivered
to the interstitium. |

Drug infusion in gel medium
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